[rtfemail]

Thanks to everyone who posted helpful info on this thread. I have been on Metformin for about 4 weeks now to manage insulin resistance issues related to PCOS. I have definitely experienced the upset stomach and diarrhea side effects. My cycle was off this month as well. Initially, my morning readings were all over the place. Some days it seemed like the metformin was working, then other days my fasting glucose was high. Just by chance, I came to discover through observation (don't ask!) that I was not always digesting my pill from the night before. So that is my new dilemna. Like one of the posters before, I am experimenting with how best to take the pill to get the benefits while minimizing the side effects. Still a work in progress....