Quote:
Originally Posted by serialmom12
Metformin is a horrible drug my poor husband was on it for 3 years. He never knew when he would vomit or have uncontrollable diarrhea. Avoid it if you can. The side effects are terrible. Januvia, Tradjenta or Glipizide are MUCH better with hardly any bad side effects except for some sore muscles Good luck.
|
Aside from the distress of GI side effects, Metformin is one of the most innocuous drugs around. The others you mentioned create the possibility of (life-threatening) hypoglycemic episodes - especially if you reduce carb consumption to control blood glucose, lactic acidosis, and put stress on the the pancreas and may be linked to pancreatitis and pancreatic cancer (both life-threatening conditions). (One study had shown "no evidence of a link," - which is not the same as establishing there is no link, especially since some of the consequences - like cancer - would be slow to develop, and will take years before we know the full story.)
If I get to the point at which I need more insulin, I would opt for Metformin and insulin supplementation. That allows for precise dosing, without straining the pancreas, and minimizing the chances for hypoglycemic episodes.