I just started Metformin 500mg twice a day about 2 weeks ago. I’ve had an ache in the middle of my back, as well as wicked leg cramps since starting the medicine. I thought it might be the Lisinopril that my doctor started me on along with the Metformin, so I stopped it for a few days and just kept taking the Metformin. I still had the leg cramps and back aches so I am certain it’s the Metformin. I hope it lessens over time.
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