Did your doctor have you increase your dosage in tiers? Mine had me increase 500 mg each week. I had no problems until I was taking metformin for over a year. I take 1000 mg daily. My problem was daytime gut bombs. I split my split 1000 in half again and took half at breakfast and half at dinner. Worked well. Zero gut bombs. Currently, I take extended release (750mg) with evening meal and 250 mg (1000 mg split in 4) and that works well too. My numbers are much better, but I'm not sure I can attribute that to this new regimen since I've also lost about 20 lbs. I can say though that the abdominal issues are gone.
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